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J Neuroradiol. 2018 Sep;45(5):276-289. doi: 10.1016/j.neurad.2018.06.003. Epub 2018 Jul 27.

Arterial spin labeling: Clinical applications.

Author information

1
Division of Neuroradiology, Mayo Clinic, 200 First St. SW, 55905 Rochester, MN, United States. Electronic address: ho.mai-lan@mayo.edu.

Abstract

Arterial spin labeling (ASL) is a magnetic resonance imaging perfusion technique that enables quantification of cerebral blood flow (CBF) without the use of intravenous gadolinium contrast. An understanding of the technical basis of ASL and physiologic variations in perfusion are important for recognizing normal variants and artifacts. Pathologic variations in perfusion can be seen in a number of disorders including acute and chronic ischemia, vasculopathy, vascular malformations, tumors, trauma, infection/inflammation, epilepsy and dementia.

KEYWORDS:

Arterial spin labeling; Cerebral blood flow; Perfusion; Postlabel delay

PMID:
30016705
DOI:
10.1016/j.neurad.2018.06.003
[Indexed for MEDLINE]

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