In this commentary, I commend and expand upon the article of Lin et al., "Racial differences in family health history knowledge of type 2 diabetes: exploring the role of interpersonal mechanisms." In particular, the commentary discusses the role and importance of culture in family health history communication, as this topic is very relevant to Lin and colleagues' primary finding that in comparison to their White counterparts, African American families had uneven distributions of family health history knowledge due to them having fewer reciprocal health communication ties. I offer insights and suggestions regarding cultural influences on family health communication and the importance of incorporating cultural considerations in family networks studies. I also provide perspective on the translation of family networks and health study findings into the types of culturally appropriate interventions needed to activate family health history communication in racial and ethnic minority families. Information discussed has implications for future efforts seeking to reduce racial and ethnic disparities in family health history communication and knowledge.