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Clin Med Insights Endocrinol Diabetes. 2018 Jun 27;11:1179551418785135. doi: 10.1177/1179551418785135. eCollection 2018.

Should Symptoms Be Considered an Indication for Parathyroidectomy in Primary Hyperparathyroidism?

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Division of Endocrine Surgery, Department of Surgery, University of Wisconsin-Madison, Madison, WI, USA.


Asymptomatic primary hyperparathyroidism is a very common endocrine condition, yet management of this disease process remains controversial. Primary hyperparathyroidism can lead to a myriad of symptoms which not only decreases the quality of life of patients but also increases the risk of cardiovascular disease, osteoporosis, and kidney stones. Parathyroidectomy is the only known cure for the disease. This review explores the definition of asymptomatic primary hyperparathyroidism, the burden of disease, and the overwhelming benefits of parathyroidectomy.


Hyperparathyroidism; asymptomatic hyperparathyroidism; benefits; parathyroidectomy; primary hyperparathyroidism; quality of life

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Declaration of conflicting interests:The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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