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Antioxidants (Basel). 2018 Jul 16;7(7). pii: E92. doi: 10.3390/antiox7070092.

Intravenous Vitamin C Administration Improved Blood Cell Counts and Health-Related Quality of Life of Patient with History of Relapsed Acute Myeloid Leukaemia.

Author information

1
Integrated Health Options Ltd., Auckland 1050, New Zealand. mfoster@integratedhealthoptions.co.nz.
2
Department of Pathology and Biomedical Science, University of Otago, Christchurch 8011, New Zealand. anitra.carr@otago.ac.nz.
3
Feedback Research Ltd., Auckland 1050, New Zealand. alina@feedbackresearch.co.nz.
4
Feedback Research Ltd., Auckland 1050, New Zealand. selene@feedbackresearch.co.nz.
5
Feedback Research Ltd., Auckland 1050, New Zealand. mike@feedbackresearch.co.nz.

Abstract

A 52-year-old female presented to Integrated Health Options Clinic in October 2014 with a history of relapsed acute myeloid leukaemia (AML, diagnosed in 2009 and relapsed in 2014). Intravenous(IV) vitamin C therapy was initiated (in 2014) following completion of chemotherapy as an alternative to haematopoietic stem cell transplantation. IV vitamin C was administered twice weekly at a dose of 70 g/infusion. Within 4 weeks of initiation of IV vitamin C therapy, there was a dramatic improvement in the patient's blood indices with platelet cell counts increasing from 25 × 10⁸/L to 196 × 10⁸/L and white blood cell counts increasing from 0.29 × 10⁸/L to 4.0 × 10⁸/L, with further improvements observed over the next 18 months. Furthermore, there was a clear and sustained improvement in the patient's health-related quality of life scores assessed using a validated questionnaire. She has remained healthy and in complete remission until the present day. This case study highlights the benefits of IV vitamin C as a supportive therapy for previously relapsed AML.

KEYWORDS:

AML; acute myeloid leukemia; intravenous vitamin C; leukemia; vitamin C

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