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Klin Monbl Augenheilkd. 2018 Aug;235(8):874-880. doi: 10.1055/a-0600-2826. Epub 2018 Jul 13.

[Clinical Evaluation of a Novel Intraocular Lens with Enhanced Depth of Focus (EDOF) to Increase Visual Acuity for Intermediate Distances].

[Article in German; Abstract available in German from the publisher]
Kretz FTA1,2,3,4, Tarib I2,3,4, Teisch S2,3,4, Kaiser I2,3,4, Lucchesi R2,3,4, Herbers C2,3,4, Hinkens A3,4, Hagen P1,5, Breyer DRH1,5.

Author information

International Vision Correction Research Centre Network (, University of Heidelberg, Heidelberg.
Augentagesklinik Rheine, Germany.
Augenärzte Gerl, Kretz & Kollegen, Ahaus, Germany.
Provisus Forschungsinstitut, Augenärzte Gerl, Kretz & Kollegen, Ahaus.
Augenchirurgie, Breyer, Kaymak & Klabe Augenchirurgie, Düsseldorf.


in English, German


Modern intraocular lens surgery has made great progress over the last few years towards creating independency of spectacles in daily life. Especially in the areas of distant and near visual acuity, optimisation has been possible. Nevertheless, with new media and requirements in professional life, there is an increasing need for optimisation of the intermediate range. In a prospective, non-randomised clinical study, the functional and refractive results after implantation of a novel intraocular lens with enhanced depth of focus were analysed.


We have evaluated eleven patients after binocular implantation of the AT LARA 829MP (Carl Zeiss Meditec AG, Germany) 3 months after surgery. We examined refraction, corrected and uncorrected monocular and binocular distant visual acuity (CDVA, UDVA) as well as distance-corrected monocular and binocular visual acuity at different intermediate distances (with DCIVA 90, 80 and 60 cm) and 40 cm (DCNVA). We also performed defocus curve analysis.


We found a mean increase of monocular CDVA from 0.35 to - 0.01 logMAR. Binocular DCIVA at 90, 80 and 60 cm was - 0.07, 0.04 and 0.07 logMAR, respectively. Even with a principle focus on intermediate distances, we found a functional DCNVA of 0.33 logMAR. Defocus curve analysis showed a visual acuity of 0.3 logMAR in a range of - 2.5 D to + 1.0 D.


Binocular implantation of the AT LARA 829MP targeting emmetropia gives stable visual acuity from the distant to the near intermediate range, still with functional vision at the near distance of 40 cm.


Conflict of interest statement

Der Bereich Klinische Forschung der Augenärzte Gerl, Kretz & Kollegen wird unterstützt von: AcuFocus, AMO/Johnson & Johnson, AVS, Carl Zeiss Meditec AG, Glaukos, Hoya, LENSAR, Mediphacos, Oculentis, PhysIOL, Polytech, Santen, Teleon.

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