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Exerc Sport Sci Rev. 2018 Oct;46(4):215-223. doi: 10.1249/JES.0000000000000161.

Protective Effects of Exercise on Cognition and Brain Health in Older Adults.

Tyndall AV1,2, Clark CM1,2, Anderson TJ3,4, Hogan DB2,5,6,7, Hill MD2,5,6, Longman RS2,8,9, Poulin MJ1,2,4,5,10,11.

Author information

1
Department of Physiology & Pharmacology.
2
Hotchkiss Brain Institute.
3
Department of Cardiac Sciences.
4
Libin Cardiovascular Institute of Alberta.
5
Departments of Clinical Neurosciences.
6
Community Health Sciences.
7
Medicine, and.
8
Psychology, University of Calgary.
9
Psychology Service, Foothills Medical Centre, Alberta Health Services.
10
Faculty of Kinesiology, University of Calgary, and.
11
O'Brien Institute for Public Health, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

Abstract

Accelerated trajectories of cognitive decline in older adults may increase the risk of developing Alzheimer disease and related dementias (ADRD). Physical activity has potential modifying effects on these changes that could prevent or delay ADRD. This review explores the hypothesis that multiple, mutually complimentary, and interacting factors explain the positive association between exercise and the optimization of cognition in older adults.

PMID:
30001269
DOI:
10.1249/JES.0000000000000161
[Indexed for MEDLINE]

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