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J Atten Disord. 2018 Jul 1:1087054718784668. doi: 10.1177/1087054718784668. [Epub ahead of print]

Concomitant Use of Psychotropic Medication With Stimulants for the Treatment of ADHD in Children and Adolescents: A Retrospective Insurance Claims Study in the United States.

Author information

1
1 Analysis Group, Inc., Boston, MA, USA.
2
2 Shire Outcomes Research & Epidemiology, Lexington, MA, USA.

Abstract

OBJECTIVE:

To evaluate annual concomitant psychotropic medication use among stimulant-treated children/adolescents with ADHD.

METHOD:

Children/adolescents with ≥1 primary ADHD diagnosis who had received ≥30 days of stimulant medication were identified from insurance claims for each calendar year (2011-2014). Use of 15 psychotropic medications concomitantly with stimulants was evaluated and their prevalence in each year was calculated overall and by medication category for children (6-12 years) and adolescents (13-17 years).

RESULTS:

Each year 133,354 to 157,303 children and 95,632 to 111,280 adolescents were included. Annual period prevalence of any concomitant psychotropic medication use was 22.9% to 25.0% for children and 25.2% to 28.2% for adolescents. The most common medication categories included selective serotonin reuptake inhibitors (children: 6.8%-7.9%; adolescents: 12.7%-14.9%), atypical antipsychotics (4.2%-5.4%; 5.3%-6.3%), and guanfacine extended release (5.1%-7.0%; 2.3%-3.6%).

CONCLUSION:

Around a quarter of children/adolescents with ADHD were prescribed psychotropic medication concomitant to stimulant treatment, although only 2 of the 15 medication classes studied were Food and Drug Administration (FDA)-approved for adjunctive use.

KEYWORDS:

ADHD; concomitant treatment; stimulants

PMID:
29991300
DOI:
10.1177/1087054718784668

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