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Prog Cardiovasc Dis. 2018 Jul - Aug;61(2):136-141. doi: 10.1016/j.pcad.2018.07.004. Epub 2018 Jul 5.

The Joint Association of Fitness and Fatness on Cardiovascular Disease Mortality: A Meta-Analysis.

Author information

1
Health and Human Performance, Middle Tennessee State University, Murfreesboro, TN, United States of America. Electronic address: Vaughn.Barry@mtsu.edu.
2
Health and Human Performance, Middle Tennessee State University, Murfreesboro, TN, United States of America.
3
Health, Exercise Science and Recreation Management, The University of Mississippi, Oxford, MS, United States of America.

Abstract

The joint association of cardiorespiratory fitness (CRF) and body mass index (BMI) on cardiovascular disease (CVD) mortality was determined. PubMed and CINAHL were searched following PRISMA guidelines. Included studies were prospective, had objective assessments of maximal CRF and BMI, and compared the joint impact of CRF and BMI on CVD mortality risk to normal weight, fit referents. Pooled hazard ratios and 95% confidence intervals were calculated from eight articles with nine independent groups using a random effects model. Unfit individuals had two to three times the risk of mortality across all levels of BMI. Overweight and obese-fit individuals had 25% and 42% increased mortality risk, respectively, compared to normal weight-fit individuals. However, for the obese-fit group, a one study removed analysis for five studies resulted in non-significant changes in mortality risk. Researchers, clinicians, and public health officials are encouraged to employ CRF interventions to reduce CDV mortality risk.

KEYWORDS:

Body mass index; Cardiorespiratory fitness; Cardiovascular disease mortality

PMID:
29981352
DOI:
10.1016/j.pcad.2018.07.004
[Indexed for MEDLINE]

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