Format

Send to

Choose Destination
Gut Pathog. 2018 Jun 22;10:25. doi: 10.1186/s13099-018-0253-x. eCollection 2018.

Tigecycline application in a 3-month-old infant with multiple drug resistant Klebsiella pneumonia: a case report.

Author information

1
Department of Neonatal Ward, Peking University First Hospital, No. 1, Xi Anmen Street, Xicheng District, Beijing, 100034 China.

Abstract

Background:

Tigecycline is an 'immature' antibiotic for children. We report the youngest surviving patient who received a complete tigecycline treatment, and no significant adverse effects occurred in the patient.

Case presentation:

The 3-month old infant suffered from a catheter-associated bloodstream infection by multiple drug resistant Klebsiella pneumoniae. Tigecycline was considered as a salvage therapy to control the severe sepsis. The therapy consisted of 3 mg/kg as a loading dose and 1.5 mg/kg Q12 h as a maintenance dose for 26 days.

Conclusion:

Current researches are limited in clinical trials directly focused on children. This therapeutic schedule might be safe for patients who are above 3 months old.

KEYWORDS:

Klebsiella pneumoniae; Multiple drug resistant; Pediatric; Tigecycline

Supplemental Content

Full text links

Icon for BioMed Central Icon for PubMed Central
Loading ...
Support Center