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Ann Pediatr Endocrinol Metab. 2018 Jun;23(2):99-102. doi: 10.6065/apem.2018.23.2.99. Epub 2018 Jun 20.

Association Kikuchi disease with Hashimoto thyroiditis: a case report and literature review.

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Department of Pediatrics, Ajou University Hospital, Ajou University School of Medicine, Suwon, Korea.


Kikuchi-Fujimoto disease (KFD) is a benign and self-limited disease characterized by fever and lymphadenopathy. The etiology of KFD is unknown, but an autoimmune cause has been suggested. Hashimoto thyroiditis is the most common autoimmune thyroid disorder in children and is known to be associated with other autoimmune diseases. Only a few cases of Hashimoto thyroiditis associated with KFD have been documented. We report a case of a 16-year-old girl who was first diagnosed with KFD and developed Hashimoto thyroiditis 2 years and 6 months later during her follow-up period. Physicians of patients with KFD should consider the possibility of autoimmune diseases like Hashimoto's thyroiditis.


Autoimmune disease; Hashimoto thyroiditis; Kikuchi-Fujimoto disease

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