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PLoS One. 2018 Jul 2;13(7):e0199581. doi: 10.1371/journal.pone.0199581. eCollection 2018.

The transverse four-chamber view for the assessment of atrial tissue deformation in the fetus.

Author information

1
Center of Pediatric Cardiology and Congenital Heart Disease, Heart- and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen, Ruhr University Bochum, Bochum, Germany.
2
Department of Pediatrics (Pediatrics I), Innsbruck Medical University, Innsbruck, Austria.
3
Department of Obstetrics and Gynecology, St. Franziskus Hospital, Münster, Germany.
4
Prenatal Medicine, Department of Obstetrics and Gynaecology, University of Münster, Münster, Germany.
5
Department of Pediatric Cardiology (Pediatrics III), Innsbruck Medical University, Innsbruck, Austria.

Abstract

AIMS:

To determine if atrial tissue deformation (peak strain, PS) and time to peak strain (TTPS) can be assessed in the fetus, with identification of best echocardiographic plane.

MATERIALS AND METHODS:

Pulsed-wave tissue Doppler study of a longitudinal and a transverse four-chamber view (FCV) in each of 20 healthy fetuses. Determination of PS and TTPS in regions of interest (ROI), viz., lateral walls of the right and left atria (RA, LA); comparison of values depending on section plane, with results-based discussion of the physiology of fetal atrial deformation and of possible clinical uses.

RESULTS:

PS and TTPS could be determined on transverse FCV in 91% of subjects and in 61% on longitudinal FCV. Transverse PS and TTPS were significantly higher than longitudinal (p = 0.0001). Transverse PS was significantly higher in RA than in LA (26.9% vs. 17.3%, p = 0.034), and transverse TTPS was significantly shorter in RA than in LA (p = 0.034).

CONCLUSION:

Atrial radial PS and TTPS determinations are possible in the fetus. The transverse FCV is best suited for these. The highest PS values and shortest TTPS values are found in ROI representing the RA. Our findings may contribute to detailed intrauterine assessment of atrial and ventricular myocardial function.

PMID:
29965971
PMCID:
PMC6028085
DOI:
10.1371/journal.pone.0199581
[Indexed for MEDLINE]
Free PMC Article

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