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J Clin Imaging Sci. 2018 May 31;8:21. doi: 10.4103/jcis.JCIS_19_18. eCollection 2018.

Benign Sclerosing and Fibrosing Conditions of the Abdomen and Their Potential Mimics.

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Department of Radiology, Gastrointestinal Imaging Group, University Hospitals of Leicester, Leicester General Hospital, Leicester, LE5 4PW, UK.
Department of Radiology, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.


The process of abnormal reparative or reactive processes in the abdominal cavity, can lead to sclerosis and fibrous deposition. The relatively recent discovery of an IgG4 subgroup of immune mediated sclerosing disease 1,2 has thrown some light on the pathophysiology of these conditions. Firstly, our pictorial review aims to describe imaging findings to enhance the general radiologist's recognition and interpretation of this varied group of benign sclerotic and fibrotic abdominal processes. Secondly, along with the imaging findings, we bring into discussion the potential mimics of these pathologic processes to minimise interpretational errors. Moreover, some of the mimics of these processes are in the spectrum of malignant disease. Most importantly, to ensure a correct diagnosis thorough clinical and histopathological assessment are required to support the imaging findings presented in this review.


Abdominal imaging; fibrosis; immunoglobulin G4; sclerosing disease

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