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Ment Health Clin. 2018 Mar 26;7(4):164-167. doi: 10.9740/mhc.2017.07.164. eCollection 2017 Jul.

Clinical pearls of gender-affirming hormone therapy in transgender patients.

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Commander, US Public Health Services, Federal Bureau of Prisons, Central Processing Pharmacy Services, Petersburg, Virginia,,
Lieutenant Commander, Chief Pharmacist, US Public Health Services, Federal Bureau of Prisons, Federal Correction Institute Otisville, Otisville, New York.


Despite the growing visibility of transgender individuals in the mainstream media, this population still encounters discrimination as well as many barriers to receiving appropriate care. Of note, not all medical providers are familiar with gender-affirming hormone treatment for transgender patients. Gender-affirming hormone treatment is used in transgender patients to reduce characteristics of their natal sex and induce those of their desired sex. Pharmacists have a potential role to make a positive impact by providing information regarding gender-affirming hormone treatment. This article aims to give an overview of the medications used in gender-affirming hormone treatment, the desired effects caused by these medications, the expected timeline to achieving these effects, and to provide information as to where these treatment guidelines can be found.


estrogen; female-to-male; gender-affirming hormone therapy; male-to-female; testosterone; transcare; transgender

Conflict of interest statement

Disclosures: The views and statements expressed in this article are solely those of the authors and do not necessarily reflect the opinions of the Federal Bureau of Prisons, US Public Health Service, or Department of Justice.

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