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Minerva Med. 2018 Aug;109(4):280-284. doi: 10.23736/S0026-4806.18.05572-6.

Benign prostatic hypertrophy: Pycnogenol® supplementation improves prostate symptoms and residual bladder volume.

Author information

1
IRVINE3 Labs, Chieti-Pescara University, Chieti, Italy.
2
International Agency for Pharma Standard Supplements (IAPPS), Chieti, Italy.
3
IRVINE3 Labs, Chieti-Pescara University, Chieti, Italy - cardres@abol.it.

Abstract

BACKGROUND:

The aim of this study was to evaluate the efficacy of Pycnogenol® supplementation in terms of safety and tolerability in the setting of preclinical or borderline, initial symptoms of benign prostatic hyperthrophy (BPH), in otherwise healthy subjects, using Pycnogenol® over a period of 60 days.

METHODS:

Seventy-five healthy men with symptoms and signs of initial BPH were included. The subjects were divided into three groups: 1) control group using only the standard management (SM); 2) a group using SM plus Pycnogenol® 150 mg/day; 3) a group using standard pharmacological management.

RESULTS:

BPH symptoms like emptying, frequency, intermittency, urgency, weak flow, straining, nocturia, were all significantly improved with Pycnogenol® (P<0.05) and the difference with both control groups was statistically significant (P<0.05).

CONCLUSIONS:

Pycnogenol® may be an important option for self-management of BPH in otherwise healthy men.

PMID:
29947491
DOI:
10.23736/S0026-4806.18.05572-6
[Indexed for MEDLINE]

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