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Mutat Res. 1985 Sep;144(1):33-9.

Induction of sister-chromatid exchanges by restriction endonucleases.

Abstract

Restriction endonucleases Cfo 1, Pvu II, Sma I, Hpa II, Taq I and Hae III were tested for their ability to induce SCEs in CHO cells. The results indicate that the DNA double-strand breaks induced during S-phase by these enzymes lead to an increase in the frequencies of SCEs.

PMID:
2993874
DOI:
10.1016/0165-7992(85)90121-6
[Indexed for MEDLINE]

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