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Chem Commun (Camb). 2018 Jul 5;54(55):7673-7676. doi: 10.1039/c8cc03574a.

Multiplexed discrimination of microRNA single nucleotide variants through triplex molecular beacon sensors.

Author information

1
School of Resource and Environmental Engineering, Hefei University of Technology, Hefei 230009, China.

Abstract

Herein, we develop a new nanopore sensing strategy for the selective detection of microRNAs and single nucleotide variants (SNVs) based on triplex molecular beacon sensors. This sensing system shows very high specificity in discriminating microRNA SNVs and can be applied for the simultaneous detection of several microRNAs of the same family in a mixture.

PMID:
29938280
DOI:
10.1039/c8cc03574a
[Indexed for MEDLINE]

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