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J Am Coll Cardiol. 2018 Jun 26;71(25):2935-2956. doi: 10.1016/j.jacc.2018.04.031.

Transcatheter Tricuspid Valve Interventions: Landscape, Challenges, and Future Directions.

Author information

1
Quebec Heart & Lung Institute, Laval University, Quebec City, Quebec, Canada.
2
Quebec Heart & Lung Institute, Laval University, Quebec City, Quebec, Canada; Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio.
3
Interventional Cardiology Unit, San Raffaele Hospital, Milan, Italy.
4
Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.
5
Quebec Heart & Lung Institute, Laval University, Quebec City, Quebec, Canada. Electronic address: josep.rodes@criucpq.ulaval.ca.

Abstract

Tricuspid regurgitation is a common finding in patients with left-sided valvular or myocardial disease, often being a marker for late-stage chronic heart failure with a grim prognosis. However, isolated tricuspid valve surgery remains infrequent and is associated with the highest mortality among all valve procedures. Hence, a largely unmet clinical need exists for less invasive therapeutic options in these patients. In recent times, multiple percutaneous therapies have been developed for treating severe tricuspid regurgitation, including tricuspid valve repair and, more recently replacement, opening an entirely new venue for managing tricuspid regurgitation. The aim of this review is to provide an updated overview and a clinical perspective on novel transcatheter tricuspid valve therapies, highlighting potential challenges and future directions.

KEYWORDS:

repair; replacement; surgery; transcatheter; tricuspid valve; tricuspid valve insufficiency

PMID:
29929618
DOI:
10.1016/j.jacc.2018.04.031

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