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Curr Protoc Mouse Biol. 2018 Jun;8(2):e44. doi: 10.1002/cpmo.44. Epub 2018 May 22.

MRI to Assess Neurological Function.

Author information

1
Mouse Imaging Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
2
Department of Medical Biophysics, The University of Toronto, Toronto, Ontario, Canada.
3
Corresponding author: jason.lerch@sickkids.ca.

Abstract

This article describes a detailed set of protocols for mouse brain imaging using MRI. We focus primarily on measuring changes in neuroanatomy, and provide both instructions for mouse preparation and details on image acquisition, image processing, and statistics. Practical details as well as theoretical considerations are provided.

KEYWORDS:

MRI; image processing; neuroscience; statistics

PMID:
29927554
DOI:
10.1002/cpmo.44
[Indexed for MEDLINE]

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