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Biochimie. 1985 May;67(5):469-73.

The missense errors in protein can be controlled by selective synonymous codon usage at the level of transcription.


In the cases of the 6-fold degenerate residues and the stop signal, selective codon usage at the level of transcription can account for a 10-20% variation in their mistranslation rate. For all other residues, the mistranslation rate is dependent upon the degree of degeneracy only, but not upon the pattern of synonymous codon usage.

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