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Echocardiography. 2018 Oct;35(10):1533-1541. doi: 10.1111/echo.14053. Epub 2018 Jun 19.

Normal reference values of diastolic strain rate in healthy individuals: Chronological trends and the comparison according to genders.

Author information

1
Division of Cardiology, Department of Internal Medicine, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.
2
Cardiovascular Center, Chungnam National University Hospital, Daejeon, Korea.
3
Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
4
Division of Cardiology, Department of Internal Medicine, Chungbuk National University School of Medicine, Cheongju, Korea.
5
Division of Cardiology, Department of Internal Medicine, Gil Hospital, Gachon University of Medicine and Science, Incheon, Korea.
6
Division of Cardiology, Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea.
7
Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
8
Division of Cardiology, Department of Internal Medicine, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju, Korea.
9
Department of Cardiology, Kyung Hee University School of Medicine, Kyung Hee University Hospital at Gangdong, Seoul, Korea.
10
Division of Cardiology, Keimyung University Dongsan Medical Center, Daegu, Korea.
11
Division of Cardiology, Department of Internal Medicine, Cardiovascular Center, Seoul National University College of Medicine, Seoul, Korea.
12
Division of Cardiology, Department of Internal Medicine, Seoul National University and Cardiovascular Center, Seoul National University Bundang Hospital, Seongnam, Korea.
13
Department of Cardiology, Ajou University School of Medicine, Suwon, Korea.
14
Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea.
15
Division of Cardiology, Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea.
16
Department of Cardiology, Chonnam National University Hospital, Gwangju, Korea.
17
Cardiovascular Center, Department of Internal Medicine, Kyung Hee University Medical Center, Seoul, Korea.

Abstract

PURPOSE:

Recently, the diastolic strain rate (DSR) utilizing speckle-tracking echocardiography has been proposed as a novel parameter for left ventricular diastolic function. We aimed to present normal reference data for those in a large-sized, selected group of healthy individuals.

METHODS:

The current study was a part of the Normal echOcardiogRaphic Measurements in KoreAn popuLation (NORMAL), a prospective nationwide survey from 23 centers in Korea. We analyzed 447 subjects (age 48 ± 15 years, 234 females) without any history of cardiovascular disease and presented the early and late DSRs (SRe and SRa , respectively) in a total and gender-/age-specified groups.

RESULTS:

Among the total subjects, the mean SRe and SRa were 1.6 ± 0.4 S-1 and 0.8 ± 0.3 S-1 , respectively. With increasing age, there were significant trends of decreasing SRe and increasing SRa . Although both gender groups showed comparable age, the female group presented significantly higher SRe compared to male subjects with age of 20-59 years, which diminished after the age of 60 years. However, the SRa was comparable between genders in all age groups. On multiple linear regression, age showed independent associations with both SRe (β = -0.132, P = .010) and SRa (β = 0.440, P < .001), whereas gender did not show any association with SRe or SRa .

CONCLUSION:

We present normal reference data of a novel parameter, DSR, in a large-sized selected group with healthy Korean subjects. Additionally, we present significant age-related changes both in SRe and SRa without the impact of their gender.

KEYWORDS:

diastolic function; diastolic strain rate; normal reference

PMID:
29920763
DOI:
10.1111/echo.14053
[Indexed for MEDLINE]

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