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AIDS. 2018 Sep 10;32(14):2077-2081. doi: 10.1097/QAD.0000000000001910.

Clinical research cerebral MRI findings in HIV-positive subjects and appropriate controls.

Author information

1
Section of Infectious Diseases, Department of Medicine, Imperial College London.
2
Department of HIV and Genitourinary Medicine, Imperial College Healthcare NHS Trust.
3
Department of Neurosciences, Imperial College London, London, UK.
4
Department of Radiology, Academic Medical Center, Amsterdam, The Netherlands.
5
Brain Research Imaging Centre.
6
Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
7
Department of Global Health, Academic Medical Center.
8
Amsterdam Institute for Global Health and Development, Amsterdam, The Netherlands.
9
Institute for Global Health, University College London, London, UK.

Abstract

: Abnormalities in cerebral MRI are frequently reported in persons living with HIV (PLWH). We compared clinical cerebral MRI reports in 59 PLWH and 29 lifestyle matched controls. Although clinical abnormalities were highly prevalent (47.7%), and included white-matter lesions (46.6%), microvascular disease (22.7%) and cerebral volume loss (11.4%), no differences were apparent between PLWH and controls, with abnormalities being associated with age and hypertension rather than HIV serostatus.

PMID:
29912060
DOI:
10.1097/QAD.0000000000001910
[Indexed for MEDLINE]

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