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Int J Dermatol. 2018 Dec;57(12):1533-1537. doi: 10.1111/ijd.14092. Epub 2018 Jun 15.

Evaluation of intralesional injection of bleomycin in the treatment of plantar warts: clinical and dermoscopic evaluation.

Author information

1
Department of Dermatology, Faculty of Medicine, Minia University, Al-Minya, Egypt.
2
Minia Dermatology Hospital, Ministry of Health, Al-Minya, Egypt.

Abstract

BACKGROUND:

Treatment of plantar warts is difficult and requires multiple treatments, and they are more refractory to treatment than common warts. Intralesional bleomycin has been used in the treatment of warts with varying degrees of success.

AIM:

The aim of the present work is to evaluate the efficacy of intralesional injection of bleomycin in the treatment of plantar warts based on clinical and dermoscopic observations.

PATIENTS AND METHODS:

Bleomycin (1 mg/ml) was injected intralesionally into the pared plantar wart every 2 weeks for a maximum of four sessions. Patients were followed both clinically and by the use of dermoscope.

RESULTS:

The cure rate of plantar warts treated with bleomycin was 69.3% with minimal and tolerable side effects.

CONCLUSION:

Intralesional injection of bleomycin is an effective and safe treatment of plantar warts. Dermoscope is recommended in the evaluation of treatment success, as it can accurately tell if the wart needs further treatment, preventing premature stoppage of the treatment, thus decreasing the possibility of recurrences.

PMID:
29907964
DOI:
10.1111/ijd.14092
[Indexed for MEDLINE]

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