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Data Brief. 2018 Mar 12;18:294-299. doi: 10.1016/j.dib.2018.03.036. eCollection 2018 Jun.

Data from a targeted proteomics approach to discover biomarkers in saliva for the clinical diagnosis of periodontitis.

Author information

1
U.F.R. d'Odontologie, Département de Parodontologie, 545 avenue du Professeur Jean-Louis Viala, 34193 Montpellier Cedex 5, France.
2
University of Montpellier, LBPC- IRMB, CHU de Montpellier, 80 rue Augustin Fliche, Montpellier, France.

Abstract

This study focused on the search for new biomarkers based on liquid chromatography-multiple reaction monitoring (LC-MRM) proteomics profiling of whole saliva from patients with periodontitis compared to healthy subjects. The LC-MRM profiling approach is a new and innovative method that has already been validated for the absolute and multiplexed quantification of biomarkers in several diseases. The dataset for this study was produced using LC-MRM to monitor protein levels in a multiplex assay, it provides clinical information on salivary biomarkers of periodontitis. The data presented here is an extension of our recently published research article (Mertens et al., 2017) [1].

KEYWORDS:

Clinical chemistry; Mass spectrometry; Oral disease; Periodontitis; Proteomics; Saliva biochemistry

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