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G Ital Dermatol Venereol. 2018 Dec;153(6):747-762. doi: 10.23736/S0392-0488.18.06093-5. Epub 2018 Jun 11.

Cutaneous squamous cell carcinoma. Italian Guidelines by SIDeMaST adapted to and updating EADO/EDF/EORTC guidelines.

Author information

1
Department of Dermatology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Sacred Heart Catholic University, Rome, Italy - ketty.peris@unicatt.it.
2
Department of Dermatology, University of Padua, Padua, Italy.
3
Dermatology Unit, University Luigi Vanvitelli, Naples, Italy.
4
Department of Dermatology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Sacred Heart Catholic University, Rome, Italy.
5
Department of Dermatology, University of L'Aquila, L'Aquila, Italy.
6
Department of Dermatology, Oncology and Prevention, Istituto Dermatologico San Gallicano, IFO, Rome, Italy.
7
Department of Dermatology, Spedali Civili di Brescia, University of Brescia, Brescia, Italy.
8
Department of Dermatology and Skin Cancer, Arcispedale S. Maria Nuova-IRCCS, Reggio Emilia, Italy.
9
Department of Dermatology, University of Modena and Reggio Emilia, Reggio Emilia, Italy.
10
Department of Dermatology, AULSS8 Berica, San Bortolo Hospital, Vicenza, Italy.
11
Section of Dermatology, Department of Surgery and Translational Medicine, Univeristy of Florence, P. Palagi Hospital, Florence, Italy.
12
Section of Dermatology, Department of Medical Sciences, University of Turin, Turin, Italy.
13
Department of Plastic Surgery, Sacred Heart Catholic University, Rome, Italy.
14
Unit of Oncological Sciences and Hematology, Sacred Heart Catholic University, Rome, Italy.
15
Department of Surgery and Translational Medicine, University of Trieste, Trieste, Italy.

Abstract

Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer, accounting for 20% of all cutaneous malignancies, and has an increasing incidence in the elderly as well as in the younger population. Although most cSCC is treated with simple therapeutic procedures, advanced cSCC can lead a significant risk for morbidity, negative impact on quality of life, and death. Proper management includes distinguishing between high-risk and low-risk lesions and determining treatment accordingly. A collaboration of multidisciplinary Italian experts has given birth to these recommendations on cSCC diagnosis and management, based on a critical review of the literature, existing European (EADO-EDF-EORTC) guidelines and the expert's experience. Topics covered include diagnostic path and histopathologic assessment, tumor staging, surgical and nonsurgical procedures, follow-up and management of localized and advanced disease.

PMID:
29898593
DOI:
10.23736/S0392-0488.18.06093-5
[Indexed for MEDLINE]
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