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Am J Epidemiol. 2018 Oct 1;187(10):2145-2150. doi: 10.1093/aje/kwy117.

Ten-Year Changes in Accelerometer-Based Physical Activity and Sedentary Time During Midlife: The CARDIA Study.

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Department of Epidemiology, Human Genetics, and Environmental Sciences and Michael & Susan Dell Center for Healthy Living, UTHealth School of Public Health, Austin Campus, Austin, Texas.
Dell Medical School, Department of Women's Health, The University of Texas at Austin, Austin, Texas.
Division of Research, Kaiser Permanente Northern California, Oakland, California.
School of Public Health, Division of Epidemiology & Community Health, University of Minnesota, Minneapolis, Minnesota.
Division of Health and Human Physiology, University of Iowa, Iowa City, Iowa.
Feinberg School of Medicine, Department of Preventive Medicine, Northwestern University, Chicago, Illinois.
Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama.
Department of Medicine, Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Division of Cardiovascular Sciences, Program in Prevention and Population Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland.


We describe 10-year changes in accelerometer-determined physical activity (PA) and sedentary time in a midlife cohort of the Coronary Artery Risk Development in Young Adults Study, within and by race and sex groups. Participants (n = 962) wore the accelerometer with valid wear (≥4 of 7 days, ≥10 hours per day) at baseline (2005-2006; ages 38-50 years) and 10-year follow-up (2015-2016; ages 48-60 years). Data were calibrated to account for accelerometer model differences. Participants (mean age = 45.0 (standard deviation, 3.5) years at baseline) had reduced accelerometer counts overall (mean = -65.5 (standard error (SE), 10.2) counts per minute/day), and within race and sex groups (all P < 0.001). Sedentary time increased overall (mean = 37.9 (SE, 3.7) minutes/day) and within race and sex groups, whereas light-intensity PA (mean = -30.6 (SE, 2.7) minutes/day) and moderate- to vigorous-intensity PA (mean = -7.5 (SE, 0.8) minutes/day) declined overall and within race and sex groups (all P < 0.001). Significant differences in 10-year change estimates were noted by race and sex groups for accelerometer counts, sedentary time, and moderate- to vigorous-intensity PA bouts; black men had the greatest reductions in PA compared with other groups. PA declines during midlife were characterized by reductions in light-intensity PA with increases in sedentary time, which may have important health consequences. Targeted efforts are needed to preserve PA, regardless of intensity level, across midlife.

[Available on 2019-10-01]

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