Format

Send to

Choose Destination
Biosensors (Basel). 2018 Jun 11;8(2). pii: E54. doi: 10.3390/bios8020054.

Aptamer-Based Biosensors for Antibiotic Detection: A Review.

Author information

1
Institute of Electronic and Sensory Materials, Faculty of Materials Science and Materials Technology, Technological University Freiberg, Akademie Str. 6, 09599 Freiberg, Germany. Asol.Mehlhorn@esm.tu-freiberg.de.
2
Institute of Electronic and Sensory Materials, Faculty of Materials Science and Materials Technology, Technological University Freiberg, Akademie Str. 6, 09599 Freiberg, Germany. Parvaneh.Rahimi@esm.tu-freiberg.de.
3
Institute of Electronic and Sensory Materials, Faculty of Materials Science and Materials Technology, Technological University Freiberg, Akademie Str. 6, 09599 Freiberg, Germany. yvonne.joseph@esm.tu-freiberg.de.

Abstract

Antibiotic resistance and, accordingly, their pollution because of uncontrolled usage has emerged as a serious problem in recent years. Hence, there is an increased demand to develop robust, easy, and sensitive methods for rapid evaluation of antibiotics and their residues. Among different analytical methods, the aptamer-based biosensors (aptasensors) have attracted considerable attention because of good selectivity, specificity, and sensitivity. This review gives an overview about recently-developed aptasensors for antibiotic detection. The use of various aptamer assays to determine different groups of antibiotics, like β-lactams, aminoglycosides, anthracyclines, chloramphenicol, (fluoro)quinolones, lincosamide, tetracyclines, and sulfonamides are presented in this paper.

KEYWORDS:

ampicillin; antibiotic; aptamer; aptasensor; biosensor; chloramphenicol; ciprofloxacin; danofloxacin; daunomycin; enrofloxacin; gentamicin; kanamycin; lincomycin; neomycin; ofloxacin; oxytetracycline; penicillin; streptomycin; sulfadimethoxine; tetracycline; tobramycin

PMID:
29891818
PMCID:
PMC6023021
DOI:
10.3390/bios8020054
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Multidisciplinary Digital Publishing Institute (MDPI) Icon for PubMed Central
Loading ...
Support Center