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Allergy. 2018 Oct;73(10):2083-2088. doi: 10.1111/all.13499. Epub 2018 Jul 9.

17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use.

Author information

1
Division of Pharmacoepidemiology and Clinical Pharmacology, Faculty of Science, Utrecht University, Utrecht, The Netherlands.
2
Department of Respiratory Medicine, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands.
3
Research Unit, Hospital Universitario N.S. de Candelaria, Universidad de La Laguna, Santa Cruz de Tenerife, Spain.
4
Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, La Laguna, Tenerife, Spain.
5
Centre for Human Molecular Genetics and Pharmacogenomics, Faculty of Medicine, University of Maribor, Maribor, Slovenia.
6
Clinic of Pediatrics, University Medical Centre Maribor, Maribor, Slovenia.
7
COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
8
Departments of Medicine, Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, USA.
9
Behavioral Sciences Institute, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico.
10
Division of Pulmonary Medicine, Allergy, and Immunology, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA.
11
Department of Biological Sciences, National University of Singapore, Singapore, Singapore.
12
The Allergy & Immunology Division, Department of Paediatric Medicine, KK Children's Hospital, Singapore, Singapore.
13
Asthma Center, Connecticut Children's Medical Center, University of Connecticut Health Center, Hartford, CT, USA.
14
Department of Women's and Children's Health, University of Liverpool, Liverpool, UK.
15
Alder Hey Children's Hospital, Liverpool, UK.
16
Department of Pediatric Pneumology and Allergy, University Children's Hospital Regensburg (KUNO), Regensburg, Germany.
17
Deptartment of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.
18
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
19
Department of Pediatrics, Sachs' Children's Hospital, Stockholm, Sweden.
20
Academic Department of Paediatrics, Brighton and Sussex Medical School, Royal Alexandra Children's Hospital, Brighton, UK.
21
Division of Molecular & Clinical Medicine, School of Medicine, University of Dundee, Dundee, UK.
22
CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.
23
Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
24
Faculty for Chemistry and Chemical Engineering, University of Maribor, Maribor, Slovenia.
25
Department of Human Genetics, Hannover Medical School, Hannover, Germany.
26
Institute of Child Health, University College London, London, UK.
27
Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
28
Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.
29
The Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
30
Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
31
Division of Respiratory Medicine, Department of Pediatrics, Sainte-Justine University Hospital Center and University of Montreal, Montreal, QC, Canada.
32
Child Health, University of Aberdeen, Aberdeen, UK.

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