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J Postgrad Med. 2018 Jun 7. doi: 10.4103/jpgm.JPGM_689_17. [Epub ahead of print]

Emphysematous osteomyelitis caused by Salmonella typhi in beta thalassemia major.

Author information

1
Department of Paediatrics, Nanavati Super Speciality Hospital, Vile Parle West, Mumbai, Maharashtra, India.
2
Department of Radiology, Nanavati Super Speciality Hospital, Vile Parle West, Mumbai, Maharashtra, India.
3
Department of Microbiology, Nanavati Super Speciality Hospital, Vile Parle West, Mumbai, Maharashtra, India.

Abstract

There have been various cases of salmonella osteomyelitis reported in sickle cell anemia. We present a case of emphysematous osteomyelitis caused by Salmonella typhi in a 29-year-old beta thalassemia major patient. Diagnosis of emphysematous osteomyelitis was confirmed by computed tomography and magnetic resonance imaging, and culture of pus drained during surgical debridement confirmed the causative microorganism, Salmonella typhi. Antimicrobials were given according to microbiological sensitivity for a period of 8 weeks. Our patient also received hyperbaric oxygen therapy. At the end of therapy, he was afebrile and laboratory parameters normalized with a residual joint deformity which developed within 3 months.

KEYWORDS:

Beta thalassemia major; Salmonella typhi; emphysematous osteomyelitis

PMID:
29882519
DOI:
10.4103/jpgm.JPGM_689_17
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