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Clin Case Rep. 2018 Apr 17;6(6):1082-1086. doi: 10.1002/ccr3.1529. eCollection 2018 Jun.

Iron deficiency without anemia - a clinical challenge.

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Outpatient clinic Eira Hospital Laivurinkatu 29 Helsinki 00150 Finland.


One should always consider iron deficiency (without anemia) as the cause of persisting, unexplained unspecific, often severe, symptoms, regardless of the primary underlying disease. The symptoms of iron deficiency may arise from the metabolic systems where many proteins are iron containing. Long-standing iron deficiency may be challenging to treat.


Anemia; ferritin; hemoglobin; iron deficiency

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