Format

Send to

Choose Destination
Chem Commun (Camb). 2018 Jun 14;54(49):6412-6415. doi: 10.1039/c8cc03475c.

Ytterbium and silver co-catalyzed synthesis of pyrrole-fused bicyclic skeletons from enynones and isocyanides.

Author information

1
Department of Chemistry, Center for Supramolecular Chemistry and Catalysis, Shanghai University, 99 Shangda Road, Shanghai, 200444, P. R. China. xsjia@mail.shu.edu.cn lijian@shu.edu.cn.

Abstract

An unusual cascade reaction of isocyanide and enynone using Yb/Ag cooperative catalysis as a key step has been disclosed. The present strategy enables the double isocyanide insertion and subsequent 5-endo-dig cyclization, thus providing a quick access to structurally complex pyrrole-fused heterocycles.

PMID:
29872777
DOI:
10.1039/c8cc03475c

Supplemental Content

Full text links

Icon for Royal Society of Chemistry
Loading ...
Support Center