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Expert Rev Pharmacoecon Outcomes Res. 2018 Jun 20:1-13. doi: 10.1080/14737167.2018.1485097. [Epub ahead of print]

Systematic review of healthcare costs related to mental health conditions among cancer survivors.

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a Division of Cancer Prevention and Control , CDC , Atlanta , United States.
b Tompkins-McCaw Library , Virginia Commonwealth University , Richmond ,  Virginia , United States.
c American Cancer Society.


This systematic review examines healthcare costs associated with mental health conditions among cancer survivors in the United States. Areas covered: Ten published studies were identified. Studies varied substantially in terms of population, mental health conditions examined, data collection methods, and type of cost reported. Cancer survivors with mental health conditions incurred significantly higher total medical costs and costs of most service types compared to cancer survivors without a mental health condition. Additionally, the total healthcare expenditure related to mental health was higher among cancer survivors compared with people without history of cancer. Expert commentary: Mental health conditions are associated with increased healthcare costs among cancer survivors. Future examination of other components of economic burden, including patient out-of-pocket costs, nonmedical costs, such as transportation, childcare, and productivity losses for patients and their caregivers, will be important. Additionally, evaluation of economic burden by cancer site, stage at diagnosis, duration of survivorship, and treatment(s) will increase understanding of the overall impact of mental health conditions on cancer survivors and on the healthcare system.


Cancer survivors; cost; economic burden; mental health; systematic review

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