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Biometals. 2018 Aug;31(4):673-678. doi: 10.1007/s10534-018-0118-2. Epub 2018 May 31.

Correlation between Na/K ratio and electron densities in blood samples of breast cancer patients.

Author information

1
Department of Medicine, Atatürk University, Erzurum, Turkey.
2
Department of Physics, Yildiz Technical University, Istanbul, Turkey.
3
Department of Chemistry, Yildiz Technical University, Istanbul, Turkey.
4
Department of Bioengineering, Sinop University, Sinop, Turkey.
5
Department of Statistics, Yildiz Technical University, Istanbul, Turkey.
6
Department of Computer Engineering, Nişantaşı University, Istanbul, Turkey.
7
Department of Nuclear Medicine, İstanbul University, Istanbul, Turkey.
8
Department of Physics, Yildiz Technical University, Istanbul, Turkey. oicelli@yildiz.edu.tr.

Abstract

The main purpose of this study was to investigate the relationship between the electron densities and Na/K ratio which has important role in breast cancer disease. Determinations of sodium and potassium concentrations in blood samples performed with inductive coupled plasma-atomic emission spectrometry. Electron density values of blood samples were determined via ZXCOM. Statistical analyses were performed for electron densities and Na/K ratio including Kolmogorov-Smirnov normality tests, Spearman's rank correlation test and Mann-Whitney U test. It was found that the electron densities significantly differ between control and breast cancer groups. In addition, statistically significant positive correlation was found between the electron density and Na/K ratios in breast cancer group.

KEYWORDS:

Blood samples; Breast cancer; Electron density; ICP-AES; Na/K ratio

PMID:
29855746
DOI:
10.1007/s10534-018-0118-2
[Indexed for MEDLINE]

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