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Poult Sci. 2018 Oct 1;97(10):3645-3651. doi: 10.3382/ps/pey219.

Antimicrobial resistance and multilocus sequence types of Campylobacter jejuni isolated from Baltic broiler chicken meat and Estonian human patients.

Author information

1
Chair of Food Hygiene and Veterinary Public Health, Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Fr. R. Kreutzwaldi 56/3, 51014, Tartu, Estonia.
2
Veterinary and Food Laboratory, Fr. R. Kreutzwaldi 30, 51006, Tartu, Estonia.
3
East-Tallinn Central Hospital, Central Laboratory, Ravi 18, 10138 Tallinn, Estonia.

Abstract

Genotypes of Campylobacter jejuni in Baltic fresh broiler chicken meat and in Estonian human origin samples were determined by using MLST. We observed associations between clonal complexes, sequence types, and antibiotic resistance of C. jejuni isolates. The detection of high proportions of fluoroquinolone resistance among Latvian (100.0%) and Lithuanian (84.6%) origin broiler chicken meat C. jejuni isolates, found in this study, suggests the wide use of these antibiotics in poultry in these countries. MLST of 48 Baltic origin C. jejuni isolates revealed a total of 22 sequence types belonging to 13 clonal complexes. From the 13 assigned CCs and 22 STs, the most prevalent were ST-353 CC and ST-5 consisting of human, Latvian and Lithuanian chicken meat isolates. Among human and chicken meat isolates the resistance rate was 63.6 and 62.2%, respectively. ST-353 isolated from humans were more often resistant to nalidixic acid and ciprofloxacin than the other STs. Strain types ST-5, ST-50, ST-353, ST-354, and ST-429 isolated from poultry were more often resistant to both nalidixic acid and ciprofloxacin than the other STs. Furthermore, ST-353 and ST-354 isolated from poultry were more often resistant against tetracycline than the other STs. Fluoroquinolone resistance was significantly (P < 0.01) associated with ST-353 CC and ST-5 in comparison with all other CCs, STs. We found that three Estonian broiler isolates belonged to the novel ST-8188.The study indicates the potential public health concern posed by the very high fluoroquinolne resistance in Campylobacter jejuni found in Latvian and Lithuanian poultry meat.

PMID:
29850847
DOI:
10.3382/ps/pey219

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