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Eur Heart J. 2018 Jun 7;39(22):2047-2062. doi: 10.1093/eurheartj/ehy077.

International Expert Consensus Document on Takotsubo Syndrome (Part II): Diagnostic Workup, Outcome, and Management.

Author information

1
University Heart Center, Department of Cardiology, University Hospital Zurich, Zurich, Switzerland.
2
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
3
Division of Cardiovascular Diseases Mayo Clinic, Rochester, MN, USA.
4
Cardiovascular Research Division, Minneapolis Heart Institute Foundation, Minneapolis, MN, USA.
5
Department of Cardiology, Hiroshima City Asa Hospital, Hiroshima, Japan.
6
Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
7
Department of Cardiovascular Sciences, Catholic University of the Sacred Heart, Rome, Italy.
8
Department of Cardiovascular Medicine, University Hospitals Leuven, Leuven, Belgium.
9
Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.
10
Department of Cardiovascular Medicine, Onga Nakama Medical Association Onga Hospital, Fukuoka, Japan.
11
Clinica Medica, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
12
University Heart Center Luebeck, Medical Clinic II, Department of Cardiology, Angiology and Intensive Care Medicine, University of Luebeck, Luebeck, Germany.
13
Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan.
14
Department of Cardiology, University Hospital Giessen, Giessen, Germany.
15
Heart Department, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", Salerno, Italy.
16
Department of Anatomy and Cell Biology, Wakayama Medical University School of Medicine, Wakayama, Japan.
17
Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua Medical School, Padova, Italy.
18
Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.
19
Division of Cardiovascular Disease, Department of Medicine, University of Florida, Gainesville, FL, USA.
20
NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital, London, UK.
21
National Heart and Lung Institute, Imperial College, London, UK.
22
Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden.
23
Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.
24
Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
25
Department of Cardiology and Intensive Care, Centre Hospitalier de Compiegne, Compiegne, France.
26
Department of Cardiology, Karolinska University Hospital, Huddinge, Stockholm, Sweden.
27
Department of Cardiology, Basil Hetzel Institute, Queen Elizabeth Hospital, University of Adelaide, Adelaide, Australia.
28
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
29
Center for Molecular Cardiology, Schlieren Campus, University of Zurich, Zurich, Switzerland.
30
Department of Cardiology, Royal Brompton & Harefield Hospital and Imperial College, London, UK.

Abstract

The clinical expert consensus statement on takotsubo syndrome (TTS) part II focuses on the diagnostic workup, outcome, and management. The recommendations are based on interpretation of the limited clinical trial data currently available and experience of international TTS experts. It summarizes the diagnostic approach, which may facilitate correct and timely diagnosis. Furthermore, the document covers areas where controversies still exist in risk stratification and management of TTS. Based on available data the document provides recommendations on optimal care of such patients for practising physicians.

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