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Crit Care. 2018 May 29;22(1):139. doi: 10.1186/s13054-018-2058-1.

The role of adrenaline in cardiopulmonary resuscitation.

Author information

1
Anaesthesia and Intensive Care Medicine, Royal United Hospital, Bath, BA1 3NG, UK.
2
Anaesthesia and Intensive Care Medicine, Royal United Hospital, Bath, BA1 3NG, UK. jerry.nolan@nhs.net.
3
Resuscitation Medicine, Bristol Medical School, University of Bristol, Bristol, UK. jerry.nolan@nhs.net.

Abstract

Adrenaline has been used in the treatment of cardiac arrest for many years. It increases the likelihood of return of spontaneous circulation (ROSC), but some studies have shown that it impairs cerebral microcirculatory flow. It is possible that better short-term survival comes at the cost of worse long-term outcomes. This narrative review summarises the rationale for using adrenaline, significant studies to date, and ongoing research.

KEYWORDS:

Adrenaline; Cardiac arrest; Cardiopulmonary resuscitation; Epinephrine; Outcome

PMID:
29843791
PMCID:
PMC5975505
DOI:
10.1186/s13054-018-2058-1
[Indexed for MEDLINE]
Free PMC Article

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