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J Perinatol. 2018 Jul;38(7):908-916. doi: 10.1038/s41372-017-0020-8. Epub 2018 May 29.

Accuracy of the Bayley-II mental development index at 2 years as a predictor of cognitive impairment at school age among children born extremely preterm.

Author information

1
Department of Pediatrics, University of North Carolina, Chapel Hill, NC, USA. moshea52@email.unc.edu.
2
Department of Psychology and Neuroanatomy, Boston University, Boston, USA.
3
Department of Neurology, Harvard Medical School, Boston, MA, USA.
4
Department of Neurology, Neuroepidemiology Unit, Boston Children's Hospital, Boston, MA, USA.
5
Department of Pediatrics, Rainbow Babies & Children's Hospital, University Hospitals Cleveland Medical Center, Cleveland, OH, 44106, USA.
6
Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
7
Division of Pediatric Neurology, Department of Pediatrics, Boston Medical Center, Boston, MA, USA.
8
Department of Psychiatry and Pediatrics, UMASS Medical School/ University of Massachusetts Memorial Children's Medical Center, Worcester, MA, USA.
9
Department of Radiology, Boston Medical Center, Boston University, Boston, USA.

Abstract

OBJECTIVE:

To describe the accuracy of the Bayley Scales of Infant Development-Second Edition (BSID-II) Mental Development Index (MDI) at 2 years of age for prediction of cognitive function at school age of children born extremely preterm.

DESIGN:

Study participants were enrolled in the Extremely Low Gestational Age Newborn Study between 2002 and 2004. Two-thirds of surviving children (nā€‰=ā€‰795) were assessed at 2 years with the BSID-II and at 10 years with an intelligence quotient (IQ) test. We computed test characteristics for a low MDI (<70), including predictive value positive.

RESULTS:

Almost two-thirds of children with a low MDI had a normal IQ (ā‰„ā€‰70) at 10 years. Concordance between MDI and IQ was highest among children with major motor and/or sensory impairment, and when MDI was adjusted for gestational age.

CONCLUSION:

Most children born extremely preterm with low BSID-II MDI at 2 years have normal intelligence at school age.

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