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Int J Impot Res. 2018 Jun;30(3):141-146. doi: 10.1038/s41443-018-0020-z. Epub 2018 May 22.

Relation between hypertension and erectile dysfunction: a meta-analysisof cross-section studies.

Author information

1
Beijing Tian Tan Hospital, Capital Medical Univercity, Neurology and Andrology Research Division, China National Clinical Research Center for Neurological Disease, 100050, Beijing, China.
2
Beijing Tian Tan Hospital, Capital Medical Univercity, Neurology and Andrology Research Division, China National Clinical Research Center for Neurological Disease, 100050, Beijing, China. 18610711834@163.com.

Abstract

Erectile dysfunction (ED) is a wide spread and troublesome problem in aging men. Many analyses of hypertensive patients suggest that the prevalence of ED in hypertensive populations is even higher. The purpose of this meta-analysis was to evaluate the relation between hypertension and ED. A literature review was performed to identify all cross-section studies about hypertension and erectile dysfunction. Sources included MEDLINE and EMBASE from 1966 to 2015. The reference lists of the retrieved studies were also investigated, and a meta-analysis were conducted. Eighteen cross-section studies involving a total of 41,943 participants and 10,151 cases of ED were used in this analysis. We found that risk of ED was increased with hypertension (summary OR = 1.84, 95% CI: 1.58-2.14, p < 0.000001). Adjusting for obesity, unfavorable lipid levels, alcohol abuse, physical activity, cigarette smoking, educational level and other lifestyle factors, hypertension was also associated with increased risk of ED (summary OR = 1.58, 95% CI: 1.35-1.86, p < 0.00001). The results of this meta-analysis support that hypertension is associated with an increased risk of ED. Further high-quality prospective studies are needed to confirm this observation.

PMID:
29785046
DOI:
10.1038/s41443-018-0020-z
[Indexed for MEDLINE]

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