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AIDS Care. 2018 Sep;30(9):1168-1172. doi: 10.1080/09540121.2018.1476659. Epub 2018 May 18.

Depression in perinatally HIV-infected pregnant women compared to non-perinatally HIV-infected and HIV-uninfected pregnant women.

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a Icahn School of Medicine at Mount Sinai , New York , NY , USA.
b Northwell Health Medical Group , Garden City , NY , USA.
c The Johns Hopkins University School of Medicine , Baltimore , MD , USA.


"Depression (as noted in chart by a physician)" was compared between HIV infected pregnant women and controls. Perinatally HIV-infected (PHIV), non-perinatally HIV-infected (NPHIV), and HIV-uninfected (HIV-U) pregnant women were all compared using a logistic regression model. Overall, HIV-infected women had higher rates of depression than HIV-U, with PHIV women demonstrating a clinically and statistically significant increased risk compared to HIV-U women [adjusted OR: 15.9, 95% CI = 1.8-143.8]. Future studies in larger populations are warranted to confirm these findings and further elucidate mental health outcomes of PHIV and NPHIV pregnant women.


Perinatally acquired HIV; depression; pregnancy

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