Format

Send to

Choose Destination
Scand J Surg. 2018 Dec;107(4):315-321. doi: 10.1177/1457496918772362. Epub 2018 May 18.

Health-Related Quality of Life after Restorative Proctocolectomy: A Cross-Sectional Study.

Author information

1
1 School of Medicine, University of Tampere, Tampere, Finland.
2
2 Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland.
3
3 School of Health Sciences, University of Tampere, Tampere, Finland.
4
4 Department of Gastroenterology, Helsinki University Hospital, Helsinki, Finland.

Abstract

BACKGROUND AND AIMS::

Patients undergoing restorative proctocolectomy have often suffered from active ulcerative colitis which should be remembered when assessing quality of life after operation. The aim of this study was to explore health-related quality of life after restorative proctocolectomy in those with poor or good pouch function and to compare that to patients with active or inactive ulcerative colitis and to the general population.

MATERIAL AND METHODS::

Altogether, 282 restorative proctocolectomy patients were investigated. The control group comprised 408 ulcerative colitis patients from the local register. Generic 15D and disease-specific inflammatory bowel disease questionnaire health-related quality of life instruments were used. Population-based data were available for 15D. Pouch function was evaluated with Öresland score and colitis activity with simple clinical colitis activity index.

RESULTS::

15D results showed that patients with good pouch function had health-related quality of life similar to that of the general population. Health-related quality of life with inflammatory bowel disease questionnaire was equally good in patients with good pouch function (n = 131; 70%) and inactive colitis (n = 95; 63%), and equally impaired in patients with poor pouch function (n = 56; 30%) and active colitis (n = 18; 12%).

CONCLUSION::

The majority of patients had health-related quality of life comparable to that in general population. Most patients with active ulcerative colitis are likely to improve their health-related quality of life after successful surgery. These findings are important when informing colitis patients about life after surgery.

KEYWORDS:

15D instrument; IPAA; Quality of life; inflammatory bowel disease questionnaire; restorative proctocolectomy; ulcerative colitis

PMID:
29774794
DOI:
10.1177/1457496918772362
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Atypon
Loading ...
Support Center