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Clin Exp Dermatol. 2018 Jul;43(5):513-517. doi: 10.1111/ced.13553. Epub 2018 May 17.

Intravenous immunoglobulins in dermatology. Part 1: biological mechanisms and methods of administration.

Author information

1
Chelsea and Westminster Hospital, London, UK.
2
Dermatological Surgery and Laser Unit, St John's Institute of Dermatology, Guy's Hospital Cancer Centre, Guy's and St Thomas NHS Foundation Trust, Great Maze Pond, London, UK.

Abstract

Intravenous immunoglobulin (IVIg) is a solution of human IgG, salt, sugars and solvents, which is used to treat a multitude of diseases. Although IVIg has been known to treat many diseases safely and successfully, there are relatively few supporting randomized controlled trials. In this article, we review the biological mechanisms of IVIg in dermatological disorders and the practicalities of its use, including its mechanism of action, dosing, availability, costs and adverse effects.

PMID:
29774583
DOI:
10.1111/ced.13553
[Indexed for MEDLINE]

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