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J Am Coll Cardiol. 2018 May 22;71(20):2346-2359. doi: 10.1016/j.jacc.2018.03.458.

Psychopharmacology and Cardiovascular Disease.

Author information

1
Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York. Electronic address: ilpina@montefiore.org.
2
Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York.
3
John Ochsner Heart and Vascular Institute, Ochsner Clinical School, New Orleans, Louisiana; The University of Queensland School of Medicine, St. Lucia, Queensland, Australia.

Abstract

This review discusses common mental health disorders and their associations with cardiovascular disease risks. Commonly found mental health disorders include depression, anxiety, and personality types. The link between depression and cardiovascular disease mortality has been established. Depression is also common in patients with heart failure. In addition to discussing psychological disorders, a review of psychotropic drugs is also included. Drugs are described for therapy for depression and anxiety, as well as associations with cardiovascular drug-drug interactions. Drug-drug interactions are more common and potentially dangerous in elderly patients, in whom the conditions often coexist. The most common drug-drug interactions involve the P450 system of enzymes.

KEYWORDS:

drug-drug interactions; psychiatric disorders; psychopharmacology

PMID:
29773162
DOI:
10.1016/j.jacc.2018.03.458

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