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Clin Immunol. 2018 Aug;193:10-11. doi: 10.1016/j.clim.2018.05.003. Epub 2018 May 14.

An anti-NMDA receptor encephalitis mimicking an HIV encephalitis.

Author information

1
Groupe Hospitalier Nord-Essonne, site Juvisy, 9 rue Camille Flammarion, 91260 Juvisy-sur-Orge, France. Electronic address: fatiha.haneche@aphp.fr.
2
AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Département de neurologie, 47-83 Boulevard de l'hôpital, 75013 Paris, France. Electronic address: sophie.demeret@aphp.fr.
3
AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Service de neurologie 2-Mazarin, 47-83 boulevard de l'hôpital, 75013 Paris, France. Electronic address: dimitri.psimaras@aphp.fr.
4
AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Service de Maladies Infectieuses et Tropicales, 47-83 boulevard de l'hôpital, 75013 Paris, France,; UPMC Sorbonne Universités, 4 Place Jussieu, 75005 Paris, France; INSERM, UMR S1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique, 56 Boulevard Vincent-Auriol, 75646 Paris, France. Electronic address: christine.katlama@aphp.fr.
5
AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Service de Maladies Infectieuses et Tropicales, 47-83 boulevard de l'hôpital, 75013 Paris, France,; UPMC Sorbonne Universités, 4 Place Jussieu, 75005 Paris, France; INSERM U1135 'HIV Pathogenesis and Immune Aging', Immunity and Infectious Diseases Research Center, 31, boulevard de l'hôpital, 75013 Paris, France. Electronic address: valerie.martinez@aphp.fr.

Abstract

The incidence of HIV associated neurocognitive disorders (HAND) were reduced with the use of antiretroviral therapy. In case of neuropsychiatric symptoms, after elimination of all infections, auto-immune encephalitis could be evocated as a differential diagnosis. We describe a case of anti-N-Methyl-d-Aspartate receptor encephalitis in an HIV-1 infected woman.

KEYWORDS:

Anti-NMDA receptor antibodies; Autoimmune encephalitis; HIV

PMID:
29772276
DOI:
10.1016/j.clim.2018.05.003
[Indexed for MEDLINE]

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