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Recenti Prog Med. 2018 May;109(5):272-293. doi: 10.1701/2902.29246.

[GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 2: Clinical practice guidelines.]

[Article in Italian]

Author information

1
Department of Health Research Methods, Evidence, and Impact (formerly Clinical Epidemiology and Biostatistics), McMaster University, Hamilton, Canada.
2
Dipartimento di Epidemiologia, Regione Lazio, ASL Roma 1.
3
Centro Nazionale Health Technology Assessment, Istituto Superiore di Sanità, Roma.
4
Dipartimento di Scienze Biomediche per la Salute, Università Statale di Milano; Unità di Epidemiologia Clinica, IRCCS Istituto Ortopedico Galeazzi, Milano.
5
Department of Health Research Methods, Evidence, and Impact (formerly Clinical Epidemiology and Biostatistics), McMaster University, Hamilton, Canada - Department of Medicine, McMaster University, Hamilton, Canada.

Abstract

In the first article in this series we described the GRADE (Grading of Recommendations Assessment, Development and Evaluation) Evidence to Decision (EtD) frameworks and their rationale for different types of decisions. In this second article, we describe the use of EtD frameworks for clinical recommendations and how it can help clinicians and patients who use those recommendations. EtD frameworks for clinical practice recommendations provide a structured and transparent approach for guideline panels. The framework helps ensure consideration of key criteria that determine whether an intervention should be recommended and that judgments are informed by the best available evidence. Frameworks are also a way for panels to make guideline users aware of the rationale (justification) for their recommendations.

PMID:
29771250
DOI:
10.1701/2902.29246
[Indexed for MEDLINE]

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