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J Clin Imaging Sci. 2018 Apr 18;8:18. doi: 10.4103/jcis.JCIS_83_17. eCollection 2018.

Renal Granulomatosis Post Intravesical Bacillus Calmette-Guerin Therapy for Non-muscle-invasive Bladder Cancer.

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1
Department of Diagnostic Radiology, University of Kentucky Chandler Medical Center, Lexington, KY, USA.

Abstract

Intravesical Bacillus Calmette-Guerin (BCG) immunotherapy is a proven, effective treatment for intermediate- and high-risk non-muscle-invasive bladder cancer. Minor side effects are common and expected but systemic effects can occur in <5% of treated patients. We present a rare case of a 49-year-old male that presented with fever and chills after 3 weeks of intravesical BCG therapy post transurethral resection of bladder tumor. New renal lesions were present on contrast-enhanced computed tomography scan which was histologically proven to be necrotizing renal granulomatosis.

KEYWORDS:

Bacillus Calmette–Guerin; non-muscle-invasive bladder cancer; renal granulomas; urothelial carcinoma

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