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J Cosmet Dermatol. 2019 Feb;18(1):169-175. doi: 10.1111/jocd.12536. Epub 2018 May 16.

Treatment of periorbital dark circles: Comparative study of carboxy therapy vs chemical peeling vs mesotherapy.

Author information

1
Alzahra Hospital, Alazhar University, Cairo, Egypt.
2
Hera Hospital, Makkah, Saudi Arabia.

Abstract

OBJECTIVE:

Evaluation and comparison of the efficacy and safety of 3 different modalities of treatment for dark circles that function via different modes of action.

METHODS:

In total, 45 female patients with periorbital hyperpigmentation were randomly selected to participate from those attending the outpatient dermatology clinic of Al-Zahraa University Hospital within a 6-month period. Patients were divided into 3 groups, and the groups were subjected to different types of therapy: group A, carboxy therapy; group B, chemical peel; and group C, vitamin C mesotherapy.

RESULTS:

No statistically significant differences were detected in improvements in pigmentation or the degree of patient satisfaction between any of the groups. However, the mesotherapy group reported more of a burning sensation following treatment than the other 2 groups but also showed a significant improvement in pigmentation and patient satisfaction compared with the carboxy group.

CONCLUSION:

All 3 treatment modalities were effective in the reduction in periorbital pigmentation. However, mesotherapy showed a significant improvement in pigmentation and a higher level of patient satisfaction compared with the other types of treatment.

KEYWORDS:

chemical peel; dark circles; mesotherapy; periorbital hyperpigmentation; vitamin C

PMID:
29767467
DOI:
10.1111/jocd.12536
[Indexed for MEDLINE]

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