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Pediatr Dermatol. 2018 Jul;35(4):494-497. doi: 10.1111/pde.13528. Epub 2018 May 15.

Primary cutaneous aspergillosis at the site of cyanoacrylate skin adhesive in a neonate.

Author information

1
Division of Pediatric and Adolescent Dermatology, Rady Children's Hospital, San Diego, CA, USA.
2
Department of Dermatology, School of Medicine University of California, San Diego, San Diego, CA, USA.
3
Department of Pediatrics, School of Medicine University of California, San Diego, San Diego, CA, USA.
4
Department of Dermatology, Southern California Permanente Medical Group, San Diego, CA, USA.

Abstract

Primary cutaneous aspergillosis is a rare but potentially life-threatening disease. We present the case of a premature infant who developed primary cutaneous aspergillosis with Aspergillus niger at the site of a skin abrasion that had been treated with a purple-colored cyanoacrylate product. The infection was treated successfully with gentle debridement of the cyanoacrylate product, followed by intravenous voriconazole and topical fluconazole. To our knowledge, this is the first reported case of primary cutaneous aspergillosis occurring at the site of cyanoacrylate-based skin adhesive.

KEYWORDS:

infection; neonatal; skin barrier; therapy

PMID:
29766554
DOI:
10.1111/pde.13528
[Indexed for MEDLINE]

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