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Pediatr Radiol. 2018 Jun;48(6):818-827. doi: 10.1007/s00247-017-4015-6. Epub 2018 May 8.

Imaging of the knee in juvenile idiopathic arthritis.

Author information

1
Department of Radiology and Nuclear Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands. r.hemke@amc.nl.
2
Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany.
3
Department of Radiology and Nuclear Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands.
4
Department of Pediatric Hematology, Immunology,Rheumatology and Infectious Disease,Emma Children's Hospital AMC, University of Amsterdam, Amsterdam, The Netherlands.
5
Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

Abstract

In juvenile idiopathic arthritis (JIA), imaging is increasingly used in clinical practice. In this paper we discuss imaging of the knee, the clinically most commonly affected joint in JIA. In the last decade, a number of important steps have been made in the development of imaging outcome measures in children with JIA knee involvement. Ultrasound is undergoing a fast validation process, which should be accomplished within the next few years. The validation processes of MRI as an imaging biomarker for clinical trials in the JIA knee are at an advanced stage, with important data available on the feasibility, reliability and validity of the Juvenile Arthritis MRI Scoring system. Moreover, both US and MRI data are emerging on the normal appearance of the growing knee joint.

KEYWORDS:

Children; Juvenile idiopathic arthritis; Knee; Magnetic resonance imaging; Radiography; Ultrasound

PMID:
29766248
PMCID:
PMC5954001
DOI:
10.1007/s00247-017-4015-6
[Indexed for MEDLINE]
Free PMC Article

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