ASSESSMENT OF FUNCTIONAL CHANGES TEAR PRODUCTION UNDER THE ACTION OF THE EYE DROPS ON THE BASE OF NATURAL MOLECULE OF ECTOINE AND ARTIFICIAL TEARS IN PATIENTS WITH DRY EYE SYNDROME ON THE BACKGROUND OF ENDOCRINE OPHTHALMOPATHY

Fiziol Zh (1994). 2016;62(6):118-121. doi: 10.15407/fz62.06.118.
[Article in English, Ukrainian]

Abstract

Conducted a comparative analysis of functional changes in tear production in patients with dry eye syndrome and endocrine ophthalmopathy in the conditions of the long-term acting of preservative free medications based on natural substances. A total of 30 people, aged 35 to 53 years old with clinical manifestations of DES on the background of EO were divided on two groups. In I group eye drops of ectoine and in II - artificial tears were administered. The examination included general and specific methods. The term of follow up - 30 days. It was found that long-term use of preservative free eye drops based on ectoine leads to more expressive positive changes in the condition of the anterior surface of the eye and the secretion and quality of the tear.

MeSH terms

  • Adult
  • Amino Acids, Diamino / administration & dosage
  • Amino Acids, Diamino / chemistry
  • Amino Acids, Diamino / therapeutic use*
  • Dry Eye Syndromes / drug therapy*
  • Dry Eye Syndromes / metabolism
  • Endocrine System Diseases / drug therapy*
  • Endocrine System Diseases / metabolism
  • Female
  • Humans
  • Lubricant Eye Drops / administration & dosage
  • Lubricant Eye Drops / chemistry
  • Lubricant Eye Drops / therapeutic use*
  • Middle Aged
  • Preservatives, Pharmaceutical
  • Tears / metabolism*
  • Treatment Outcome

Substances

  • Amino Acids, Diamino
  • Lubricant Eye Drops
  • Preservatives, Pharmaceutical
  • ectoine