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Int J Toxicol. 2018 May/Jun;37(1_suppl):55S-66S. doi: 10.1177/1091581818776013.

Safety Assessment of Hydrolyzed Wheat Protein and Hydrolyzed Wheat Gluten as Used in Cosmetics.

Author information

1
1 Scientific Analyst/Writer, Cosmetic Ingredient Review, Cosmetic Ingredient Review, Washington, DC, USA.
2
2 Expert Panel Member, Cosmetic Ingredient Review, Cosmetic Ingredient Review, Washington, DC, USA.
3
3 Former Director, Cosmetic Ingredient Review, Cosmetic Ingredient Review, Washington, DC, USA.
4
4 Executive Director, Cosmetic Ingredient Review, Washington, DC, USA.

Abstract

The Cosmetic Ingredient Review (CIR) Expert Panel (Panel) reviewed the product use, formulation, and safety data on hydrolyzed wheat protein and hydrolyzed wheat gluten, which function as skin- and hair-conditioning agents. The Panel determined that data from clinical and laboratory studies were sufficient to demonstrate that these ingredients will not elicit type 1 immediate hypersensitivity reactions in sensitized individuals and will not induce sensitization when the polypeptide lengths of the hydrolysates do not exceed 30 amino acids. The Panel concluded that hydrolyzed wheat gluten and hydrolyzed wheat protein are safe for use in cosmetics when formulated to restrict peptides to an average molecular weight of 3,500 Da or less.

KEYWORDS:

cosmetics; hydrolyzed wheat gluten; hydrolyzed wheat protein; safety

PMID:
29761728
DOI:
10.1177/1091581818776013
[Indexed for MEDLINE]

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