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Acta Radiol. 2019 Feb;60(2):149-159. doi: 10.1177/0284185118774956. Epub 2018 May 14.

Diagnostic accuracy of dual-source and 320-row computed tomography angiography in detecting coronary in-stent restenosis: a systematic review and meta-analysis.

Author information

1
1 Department of Radiology, First Hospital of LanZhou University, Lanzhou, Gansu, PR China.
2
2 Department of Anesthesia, First Hospital of LanZhou University, Lanzhou, Gansu, PR China.

Abstract

BACKGROUND:

Dual-source and 320-row computed tomography angiography (CTA) are increasingly used in diagnosing coronary in-stent restenosis (CISR).

PURPOSE:

We sought to perform this meta-analysis to evaluate the diagnostic accuracy of dual-source computed tomography angiography (DSCTA) and 320-row CTA in detecting CISR when compared to invasive coronary angiography.

MATERIAL AND METHODS:

Five scientific databases (PubMed, Embase, Scopus, The Cochrane Library, and Web of Science) were searched for research studies in which DSCTA and/or 320-row CTA were used as diagnostic tools for CISR, as recently as October 2017. Study inclusion, data extraction, systematic review, pooled meta-analysis, and subgroup analysis were conducted by two researchers independently.

RESULTS:

Thirteen studies with 1384 assessable stents on DSCTA and five studies including 622 assessable stents on 320-row CTA were finally included. The sensitivity, specificity, and area under the curve (AUC) of DSCTA in diagnosing CISR were 0.92 (0.87-0.96), 0.91 (0.87-0.94), and 0.97 (0.95-0.98), respectively, and they were 0.91 (0.82-0.96), 0.95 (0.88-0.98), and 0.96 (0.94-0.97) for 320-row CTA. Subgroup analysis result suggested that DSTCA performed significantly better in CISR detection when the stent diameter was ≥ 3 mm compared to stent diameter < 3 mm: 0.98 (0.97-0.99) vs. 0.82 (0.79-0.86) with P < 0.05.

CONCLUSION:

Our meta-analysis indicated both DSCTA and 320-row CTA had high diagnostic accuracy in detecting CISR and may serve as alternatives for further patient evaluation with CISR, especially for stent diameters ≥ 3 mm.

KEYWORDS:

320-row; Dual-source computed tomography angiography (DSCTA); coronary in-stent restenosis (CISR); meta-analysis

PMID:
29758995
DOI:
10.1177/0284185118774956
[Indexed for MEDLINE]

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